Muscular dystrophy is the name given to a group of inherited conditions where there is a progressive wasting and weakening of muscle. Limb-girdle muscular dystrophy generally causes weakness in the shoulder and pelvic girdle. Usually weakness of the legs is noticed before that of the arms and usually the muscle of the face are unaffected.
Features of LGMD are presented differently in different people, but common features can be frequent falls, difficulty in running, climbing stairs and ring from the floor.
As the condition progresses people may have trouble walking and may need to use a wheelchair. Shouder and arms muscle weakness means that they may have difficulty raising their arms above their head and in lifting objects. In some cases the heart and breathing muscles can be affected.